Side effects

• pain, swelling or redness at the injection site are common and may occur more frequently following subsequent doses
• a small, painless nodule may form at the injection site; this usually disappears and is of no consequence
  • incidence of local reactions is lower with tetanus vaccines combined with acellular pertussis vaccines than with whole-cell pertussis vaccines, and similar to that after diphtheria (DT) vaccine
    
    
• fever, convulsions, high-pitched screaming, and episodes of pallor, cyanosis and limpness occur with equal frequency after both DTaP and DT vaccines
• confirmed anaphylaxis occurs extremely rarely
• other allergic conditions may occur more commonly and are not contraindications to further immunisation (1)
  
  
• Hib/Men C conjugate vaccine
  • mild side effects such as irritability, loss of appetite, pain, swelling, redness at the site of the injection and slighty raised temperature commonly occur
  • less commonly, crying, diarrhoea, vomiting, atopic dermatitis, malaise and fever over 39.5°C have been reported

Check The Green Book for uptodate details.

Check the Summary of Product Characteristics before prescribing/administering a Hib-containing vaccine.

Reference:

1. Immunisation Against Infectious Disease - "The Green Book".Chapter 16 Haemophilis influenzae type B (Hib) (April 2019)