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Methods

Authoring team

The trial design was:

  • multicentre
  • randomised
  • double-blind
  • double-dummy

449 patients were enrolled into the trial within 30 hours from the onset of symptoms. Haemorrhagic stroke was excluded by a CT scan.

  • the aspirin group received 160 mg daily
  • LMWH group received 100 IU/kg twice daily

Patients were assessed at day 14 for:

  • recurrent stroke
  • secondary endpoints:
    • cerebral haemorrhage
    • progression of symptoms within the first 48 hrs
    • death

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