This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Polycystic ovarian syndrome (and impaired glucose tolerance)

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • prevalence study of a cohort of women with PCOS (1)
  • 122 women with PCOS were recruited from hospital clinics
    • a prospective study was undertaken with a subset of 25 women to determine the natural history of glucose intolerance in PCOS.
  • an oral glucose tolerance test was undertaken - 10% of women had type 2 diabetes and 35% had impaired glucose tolerance.
  • a repeat oral glucose tolerance test was performed on the subset of 25 women after a mean follow-up of 2.4 years; two-hour glucose levels were higher (significance level p<0.02) but in some of the women glucose tolerances had improved

There is evidence that for patients with PCOS, Sex hormone binding globulin (SHBG) is an integrated marker of insulin resistance that may be of use to identify insulin-resistant individuals (2).

Screening for glucose intolerance (3):

  • it is recommended that women presenting with PCOS, particularly if they are obese (BMI>30), have a strong family history of type 2 diabetes, or are over the age of 40 years, be offered a glucose tolerance test as they are at increased risk for type 2 diabetes
  • annual fasting glucose may be useful in screening for diabetes in women with PCOS. If the fasting glucose is >=5.6 mmol/l and the patient has other risk factors for diabetes, an oral glucose tolerance test is recommended


Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page