Calculation of warfarin maintenance dose based on rapid anticoagulation regime with 10mg initial dose
This is based on the INR taken on the morning of day 4, ie after 3 doses of warfarin. Check with local guidance before prescribing.
Example guidance:
INR | Predicted maintenance dose
|
< 1.4
| >8 |
1.4 | 8 |
1.5 | 7.5 |
1.6-1.7 | 7 |
1.8 | 6.5 |
1.9 | 6 |
2.0-2.3 | 5.5 |
2.4-2.6 | 4.5 |
2.7-3.0 | 4 |
3.1-3.5 | 3.5 |
3.6-4.0 | 3 |
4.1-4.5 | miss out next day's dose then 2mg per day |
>4.5 | miss out next two days' dose then 1mg per day |
Reference
- Guidelines on oral anticoagulation with warfarin, British Committee for Standards in Haematology (2011)
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