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ATP synthase

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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ATP synthase is a large enzyme found in the inner mitochondrial membrane. It is divided into:

  • F1 head section
  • F0 proton channel

It is vital for the transduction of a proton gradient into the energy held within the terminal phosphate bond of ATP during oxidative phosphorylation. Protons pass down the proton channel along their chemiosmotic gradient and simultaneously induce a change in the head section. The configurational change triggers the reaction: ADP + inorganic phosphate -> ATP.

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