Treatment and prevention
Praziquantal - not licensed for human use in the UK - is the treatment of choice for Clonorchiasis. The World Health Organization (WHO) recommends 25 mg/kg orally 3 times daily for 2 to 3 days or 40mg/kg in a single administration, resulting in cure rates above 90%. (1)
An alternative regimen is albendazole (10mg/kg) for 5 to 7 days. (2)
Cholangitis is treated with intravenous antibiotics.
Surgery may be required for the physical removal of worms and/or stones if obstruction persists.
Infection is prevented by thorough cooking of fish.
References
- Xu LL et al. Efficacy and safety of praziquantel, tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths. PLoS Negl Trop Dis. 2014 Aug;8(8):e3046.
- Qian MB, Utzinger J, Keiser J, Zhou XN. Clonorchiasis. Lancet. 2016 Feb 20;387(10020):800-10
Create an account to add page annotations
Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page