This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Drugs induced raised or high alk phos

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

There are many drugs (1,2) that may result in a raised alkaline phosphatase. It is important to consider that a medication may be the cause of an isolated raised alkaline phosphatase - but also consider other possible causes as well.

Some examples of drugs that may cause a raised alkaline phosphatase include:

  • Antibiotics:
    • penicillin derivatives (1)
    • nitrofurantoin
    • erythromycin
    • aminoglycosides (1)
    • sulfonamides (2)
    • trimethoprim-sulfamethoxazole (2)

  • Antiepileptic drugs:
    • Carbamazepine
    • Phenobarbital
    • Phenytoin
    • Valproic Acid

  • Antihistamines:
    • Cetirizine (1)

  • Cardiovascular drugs:
    • Captopril (1)
    • Diltiazem
    • Felodipine (1)
    • Verapamil (2)
    • Quinidine (2)
    • Flutamide (2)

  • Disease modifying agents:
    • Penicillamine
    • Sulfa drugs (1)
    • Gold salts (2)

  • Polycyclic aromatic hydrocarbons:
    • Oestrogens
    • Anabolic Steroids (2)
    • Steroids (1)
    • Methyltestosterone (2)

  • Psychotropic drugs:
    • Monoamine oxidase inhibitors
    • Phenothiazines e.g. chlorpromazine (1,2)

  • Diabetes drugs:
    • tolbutamide
    • chlorpropamide
    • tolazamide

  • Other drugs:
    • Allopurinol
    • Methimazole
    • Disulfiram
    • Phenylbutazone


Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.


Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.