Methyl dopa
Methyl dopa is a centrally-acting antihypertensive drug that is gradually declining in usage. It inhibits decarboxylation of dopa to dopamine. Therapy is associated with reduced concentrations of dopamine, 5 - hydroxytryptamine and noradrenaline in peripheral tissues and the CNS. This drug is associated with a reduction in renin levels.
Indications for the use of methyl dopa include:
- hypertension, in conjunction with a diuretic
- hypertensive crisis when an immediate effect is not necessary
Cautions/Contraindications:
- history of depression
- active liver disease
- porphyria
- phaeochromocytoma
- increases the CNS toxicity of lithium
Related pages
Create an account to add page annotations
Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page