Epidemiology
Peptic ulcers account for up to 10% of hospital admissions. It is a common condition - there is a lifetime incidence of up to 10%.
The mortality rate is 1 in 100,000, a figure which has decreased modestly in the last few decades.(1)
In the developed world, H pylori incidence has been slowly declining over the past 50 years and NSAID use has increased. Most studies report that peptic ulcers are decreasing in prevalence over time (2)
Reference:
- Prabhu V, Shivani A. An overview of history, pathogenesis and treatment of perforated peptic ulcer disease with evaluation of prognostic scoring in adults. Ann Med Health Sci Res. 2014 Jan;4(1):22-9.
- Azhari H, King JA, Coward S, et al. The global incidence of peptic ulcer disease is decreasing since the turn of the 21st century: a study of the Organisation for Economic Co-Operation and Development (OECD). Am J Gastroenterol. 2022 Sep 1;117(9):1419-27.
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