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Epidemiology

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Perforated peptic ulcer occurs in men more then women and has its highest incidence in the 40 to 60 year age groups.

Other epidemiological points of note:

  • often associated with NSAIDs or steroid treatment in patients with peptic ulcer disease
  • more rarely associated with stress such as trauma and major burns
  • perforations of duodenal ulcers are three times more common than gastric ulcer perforations
  • gastric ulcer perforations are:
    • uncommon
    • most common in the elderly
    • in a third due to perforation of a gastric carcinoma
  • oesophageal peptic ulcers are a very rare cause of peptic ulcer perforation

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