Associated diseases
84% of patients with primary biliary cirrhosis have at least one other autoimmune disease.
These include:
- autoimmune thyroiditis
- Sjogren's syndrome
- CREST syndrome
- scleroderma
- rheumatoid arthritis
- fibrosing alveolitis
Rarer associations include:
- jejunal villous atrophy
- bullous pemphigoid
- capillaritis
- lichen planus
- IgM-associaed membranous glomerulonephritis
- renal tubular acidosis
- dermatomyositis
- polymyositis
- mixed connective tissue disease
- systemic lupus erythematosus
- Grave's disease
- ulcerative colitis
- autoimmune thrombocytopaenia
- breast cancer - there is a four fold increase in incidence in women with PBC
Note:
- natural history or clinical presentation of PBC is not modified by autoimmune comorbidities (1)
Reference:
Related pages
- Nutritional causes
- Endocrine causes
- CREST syndrome
- Rheumatoid arthritis
- Bullous pemphigoid
- Lichen planus
- Renal tubular acidosis
- Polymyositis and dermatomyositis
- Mixed connective tissue disease
- Systemic lupus erythematosus (SLE)
- Graves' disease
- Idiopathic thrombocytopenic purpura
- Ulcerative colitis (UC)
- Breast cancer
- Cryptogenic fibrosing alveolitis
- Vanishing bile duct syndrome (VBDS) (ductopenia)
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