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Via indirect alteration of an endogenous agonist

Authoring team

Drugs may act via an indirect alteration of the effect of an endogenous agonist as follows:

  • physiological antagonism - glucagon vs insulin
  • increase in endogenous release - Ecstasy
  • inhibition of endogenous re-uptake - tricyclics
  • inhibition of endogenous metabolism - selegiline
  • prevention of endogenous release - chromoglycate

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