This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Indications for liver transplantation

Authoring team

If the acute management of paracetamol poisoning is ineffective and fulminant hepatic necrosis ensues then liver transplantation is life-saving.

The indications for liver transplantation are:

  • acidosis (pH < 7.3), or
  • all of the following:
    • PT > 100 sec
    • creatinine > 300 mcg/l
    • grade 3 encephalopathy (or worse)

It is better to contact the local liver transplant centre earlier than this. Grossly abnormal prothrombin times should trigger referral:

  • PT > 20 sec at 24 hr
  • PT > 40 sec at 48 hr
  • if PT is between 20 and 40 sec at 48 hr then check the PT again at 72 hr; if PT is still > 20 sec then refer

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.