Side effects
- dose related: gastric irritation, nausea, postural tremor, involuntary movements, thrombocytopenia.
- idiosyncratic: nausea, vomiting, anorexia, transient hair loss, impaired liver function leading rarely to liver failure.
- long term: weight gain (females)
- others: hyperammonaemia, ammenorrhoea, rashes, pancreatitis, leucopenia, red cell hypoplasia, in pregnant mothers - increased risk (x20) of infant with spina bifida
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