Normal or raised TSH, raised free thyroid hormones
Normal or elevated TSH in the presence of raised free thyroid hormones is a rare disorder but may be clinically important.
The causes of this pattern of abnormality are:
- artefact - need to repeat the tests
- interfering antibodies
- familial dysalbuminaemic hyperthyroxinaemia
- amiodarone therapy
- thyroid hormone receptor mutations
- acute psychiatric disease
- TSH secreting pituitary tumour
- intermittent thyroxine overdosing
Reference:
- Thyroid Function Tests. British Thyroid Foundation, revised 2021
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