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WBC abnormal

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The leukocytes are blood cells possessing a nucleus.

There are three key types - granulocytes, lymphocytes, monocytes::

  • granulocytes
    • a group of white blood cells defined on the basis of their granular appearance on microscopic examination after application of Romanowsky stains. They are all derived from a promyelocyte precursor within the bone marrow by granulopoiesis. Granulocytes include:
      • neutrophils - polymorphonuclear leukocytes
      • basophils
      • eosinophils

  • lymphocytes

  • monocytes

They are involved in inflammatory and immune responses.

A schemata for managing raised neutrophils, lymphocytes or monocytes in adults is presented (1):

 

Detailed flowchart explaining lymphocyte and neutrophil levels in blood tests, outlining conditions associated with abnormal levels and subsequent medical referrals or tests recommended.

If raised eosinophil count in an adult (1):

 

Flowchart detailing the diagnostic approach and considerations for Eosinophilia, including blood tests, possible causes, and when to refer to a haematologist.

Reference:

  • NHS Camden CCG. Abnormal FBC guidance - for adults (Accessed 30/10/19)

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