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Management of infertility

Authoring team

Male factors - loose clothing, abstinence from hot baths, clomiphene, intrauterine or donor insemination.

Ovulatory dysfunction - clomiphene citrate, gonadotrophins, pulsatile GnRH, bromocriptine.

Luteal phase deficiency - progesterone, clomiphene.

Tubal damage - surgery.

Cervical factor - bicarbonate douches, intrauterine insemination.

Endometriosis - laparoscopic ablation may increase fecundity in the short term i.e. the capacity to become pregnant, but not long term fertility rates. Assisted reproduction may be advised especially as it will bypass any peritoneal presence of inhibitory factors to gamete function.

NICE suggest (1):

Flowchart illustrating assessment and treatment pathways for various fertility problems, categorized by cause (e.g., endometriosis, age, male factor), outlining steps from initial advice to advanced treatments.

Reference

  1. NICE. Fertility problems: assessment and treatment. Clinical guideline CG156. Published February 2013, last updated March 2026

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