progestogens may affect foetal liver function. The use of progestogens of the nortestosterone family e.g. norethisterone, may cause masculinization of the female foetus
antithyroid medication may cause cretinism
corticosteroids (1):
use of corticosteroids for prolonged periods or repeatedly in pregnancy is associated with intra-uterine growth retardation (IUGR) in the foetus
no convincing evidence that systemic corticosteroids cause an increased risk of congenital abnormalities such as cleft lip or palate
prednisolone is excreted in small amounts into breast milk. However, systemic effects in the infant are unlikely with doses of up to 40mg of prednisolone or equivalent; infants should be monitored for adrenal suppression if the mothers are taking a higher dose
stilboestrol this drug has been linked to the subsequent development of vaginal carcinoma and adenosis in teenagers if their mothers received the drug during pregnancy
Reference:
Current Problems in Pharmacovigilance (1998), 24, 9.
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