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Spironolactone in hypertension

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • suggested to add a low dose of spironolactone as the 4th line agent in hypertension management in those whose serum potassium is <4.5 mmol/L and whose eGFR is >45 ml/min/1.73m2 to achieve BP targets

  • avoid use with K+ supplements, other K+-sparing diuretics, or significant renal dysfunction

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