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Switching options for women taking sequential HRT preparations with transdermal oestradiol

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Women taking sequential HRT preparations with transdermal oestradiol can consider the following options below:

  • Evorel Sequi patches
    • provides transdermal oestradiol with sequential progestogen (norethisterone)
    • alternatively, women can consider transdermal oestrogen delivery with an alternative progestogen by taking oestrogen and progestogen separately:
      • Oestrogen:
        • Evorel 50 patches
        • Estradot 50 patches
        • Estraderm 50 patches
        • Femseven mono 50 patches
        • Progynova TS 50 patches
      • Or an oestradiol gel preparation such as Oestrogel or Sandrena:
        • Oestrogel one measure twice a day would be equivalent to the oestrogen dose in Evorel Sequi
        • Or Sandrena 1mg sachet a day would be equivalent to the oestrogen dose in Evorel Sequi
        • Or oestradiol spray Lenzetto three sprays (40 mcgm) would be equivalent to the oestrogen dose in Evorel Sequi

      • Progestogen:
        • Micronised Progesterone: Utrogestan 200mg orally for 12 days a month at night (cyclical)
        • Or Provera 10mg orally for 12 days a month
        • Or Norethisterone 5mg orally for 12 days a month
        • Or Mirena IUS

Reference:


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