Differential diagnosis
The differential diagnosis of CLL includes:
- benign causes
- B cell
- postsplenectomy
- T cell
- bacterial (TB, syphilis) and viral (infectious mononucleosis, CMV) infections
- serum sickness
- thyrotoxicosis
- postsplenectomy
- B cell
- malignant causes
- B cell
- prolymphocytic leukaemia
- leukaemic phase of non-Hodgkin lymphoma
- mantle cell lymphoma
- marginal zone lymphoma
- hairy cell leukaemia
- Waldenstrom's macroglobulinaemia
- T cell
- T cell prolymphocytic leukaemia
- prolymphocytic leukaemia
- adult T cell leukaemia/lymphoma (1)
- B cell
Reference:
- Eichhorst B, Robak T, Montserrat E, et al; ESMO Guidelines Committee. Chronic lymphocytic leukaemia: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2021 Jan;32(1):23-33.
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