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Essential cryoglobulinaemia

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Idiopathic cryoglobulinaemia may be associated with a necrotising polyarteritis. It is characterised by:

  • absence of underlying systemic illness
  • palpable purpura
  • arthralgia
  • weakness
  • hepatosplenomegaly
  • diffuse proliferative glomerulonephritis

It is usually a mixed type cryoglobulinaemia, type I or II.

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