Differential diagnosis of acute leukaemia
The differential diagnosis of acute leukaemia includes:
- if lymphadenopathy present:
- lymphoma
- Epstein-Barr virus infection
- if hepatosplenomegaly present:
- myeloproliferative disorder
- lymphoproliferative disorder
- myelodysplasia
- metabolic and storage disorders
- autoimmune disorders
- pancytopenia without peripheral blast cells:
- aplastic anaemia
- marrow infiltration by tumour
- myelodysplasia
Reference:
- Lyengar V et al. Leukemia. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan. 2023 Jan 17.
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