Leukaemia (chronic T-cell lymphocytic)
Lymphocytes of T cell origin are seen in 1% of patients with CLL.
Patients tend to be younger than those with B cell CLL and lymphadenopathy less prominent. Circulating lymphocytes have abundant cytoplasm with azurophilic granules and T cell markers.
Treatment is largely ineffective compared to B cell CLL with consequent poorer prognosis.
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