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Neutrophilia

Authoring team

Neutrophils comprise approximately 40% to 60% of the total leukocyte count. Neutrophilia, an increased neutrophil count at least 2 standard deviations above the mean or >7700 neutrophils/µL in adults, is the most common cause of leucocytosis. (1)

Neutrophils > 7.5 x 109/l may be caused by:

  • bacterial infection
  • surgery
  • burns
  • trauma
  • haemorrhage
  • infarction
  • inflammation
  • polymyalgia
  • myeloproliferative disorders
  • leukaemias
  • polyarteritis nodosa
  • drugs e.g. steroids

A suggested management of raised neutrophils in adults is:

 

Flowchart detailing normal and raised neutrophil levels with potential causes and recommended medical actions

Reference

  1. Riley LK, Rupert J. Evaluation of Patients with Leukocytosis. Am Fam Physician. 2015 Dec 01;92(11):1004-11

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