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Drug therapy in chronic myeloid leukaemia

Last reviewed 19 Mar 2025

Authoring team

The drugs used in the treatment of the chronic phase of CML are:

imatinib
alfa interferon
hydroxyurea
busulphan
newer tyrosine kinase inhibitors - Dasatinib, Nilotinib for imatinib-resistant CML (1)

Transformed CML may respond to chemotherapy regimes developed for acute leukaemias.

Reference:

(1) O'Brien S et al. NCCN clinical practice guidelines in oncology: chronic myelogenous leukemia. J Natl Compr Canc Netw. 2009;7(9):984-1023.

Recombinant alpha interferon in CML
Hydroxyurea in CML
Busulphan in CML
Treatment of transformed leukaemia

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Drug therapy in chronic myeloid leukaemia

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