Type III cryoglobulin
Type III cryoglobulins are a polyclonal cryoglobulin in association with a polyclonal rheumatoid factor. The immunoglobulin composition include:
- IgM-IgG
- IgM-IgG-IgA
The clinical associations with a type III cryoglobulinaemia include:
- SLE
- rheumatoid arthritis
- EBV
- Sjogren's disease
- CMV
- hepatitis B
- infective endocarditis
- Kala-azar
- leprosy
- primary biliary cirrhosis
- post-streptococcal nephritis
Reference
- Roccatello D, Saadoun D, Ramos-Casals M, et al. Cryoglobulinaemia. Nat Rev Dis Primers. 2018 Aug 2;4(1):11.
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