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Laboratory findings

Authoring team

  • prolonged prothrombin time
  • prolonged partial thromboplastin time - but less so than for PT
  • fibrinogen level, thrombin time and platelet count are unaffected

If the prothrombin time is prolonged, there are two alternatives for determining if vitamin K deficiency is the cause:

  • positive response to therapeutic trial of vitamin K supplements
  • plasma radioimmunoassay of the non-carboxylated precursor of prothrombin; shown to be at increased concentration

 

Reference

  1. Rina E. Eden; Sharon F. Daley; Jean M. Coviello. Vitamin K Deficiency. StatPearls Publishing. 2024 Jan

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