Antifungal agents

Antifungal agents represent a pharmacologically diverse group of drugs that are crucial components in the modern medical management of mycoses. While antimycotic pharmacology has advanced significantly, particularly in the last three decades, common invasive fungal infections still carry a high mortality rate:

Candida albicans (approximately 20 to 40% mortality)

Aspergillus fumigatus (approximately 50 to 90%)

Cryptococcus neoformans (approximately 20 to 70%)

Reference

1. Lai CC, Tan CK, Huang YT, Shao PL, Hsueh PR. Current challenges in the management of invasive fungal infections. J Infect Chemother. 2008 Apr;14(2):77-85.