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Treatment

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Acute disease - treatment with nifurtimox or benzidiazole:

  • benznidazole
    • is considered first-line therapy because it usually causes fewer side effects and has more evidence of effectiveness than nifurtimox (1)
    • people with Chagas disease should be treated with benznidazole for 60 days and monitored regularly for side effects (1)

Chronic disease is treated symptomatically. There is no evidence that drug treatment alters the natural course of the disease.

Reference:

  1. Clark EH, Bern C. Chronic Chagas disease in the US. JAMA. 2024;331(23):2037-2038

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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