The following drugs affect histamine synthesis, release, action at post-synaptic receptors, or mimic the action of histamine:
- H2-receptor antagonists, used in:
- peptic ulceration
- peptic oesophagitis
- Zollinger-Ellison syndrome
- undiagnosed dyspepsia
- treatment of NSAID-associated ulcers
- preventing erosions in hepatic coma patients
- preventing acid aspiration in obstetric patients at delivery
- mast cell-stabilizers: used in asthma with an allergic basis, particularly in children
- antihistamines, used in:
- treatment of nasal allergies
- preventing and treating urticaria, pruritus, insect bites and stings, and drug allergies
- as an adjunct to the treatment of anaphylaxis
- the treatment of vestibular disorders including motion sickness and Meniere's disease