Skeletal disorders
The commonest skeletal disorder is dysostosis multiplex:
- bone formation is abnormal in the metaphysis, diaphysis and epiphysis
- radiographs demonstrate:
- oar shaped ribs - the flattened end at the sternum
- enlarged diaphyses and roughened epiphysial centres
- anterior beaking of the vertebrae
- odontoid hypoplasia
- rarely, spinal dislocation
Patients, notably with Gaucher's disease, may suffer vascular damage to bone such as avascular necrosis of the femoral head.
Related pages
Create an account to add page annotations
Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page