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Fungal infections of the nervous system

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Fungal infection of the nervous system usually occurs in patients with impaired immunity.

Classically the most common pathogens were candida and aspergillus; with the advent of AIDS, cryptococcal infection has become more frequent.

Clinically there are two main presentations:

  • meningitis, often subacute
  • multifocal encephalitis

One should look for fungal infection elsewhere, such as skin or lung.

Diagnosis usually comes from analysis of cerebrospinal fluid or biopsy tissue.

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