Diagnosis

Diagnosis is usually based on clinical grounds (1).

Diagnosing techniques include:

• Coxsackie A (generally A16) virus is isolated from lesions and stools
• serum testing may reveal a specific antibody (1,2)

References:

1. Saguil A, Kane SF, Lauters R, et al. Hand-foot-and-mouth disease: rapid evidence review. Am Fam Physician. 2019 Oct 1;100(7):408-14.
2. Ooi M et al. Evaluation of Different Clinical Sample Types 1 in the Diagnosis of Human Enterovirus 71 Associated Hand-Foot-and-Mouth Disease. J. Clin. Microbiol. 2007;45:1858-1866