This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Clinical presentation

Authoring team

presentation

Japanese Encephalitis (JE) is primarily a disease of children (although all age groups can be affected)

  • most adults in endemic countries have natural immunity after childhood infection (1)

The incubation period is from 5 to 15 days:

  • in survivors, the illness may range from asymptomatic infection to severe encephalitis with a high mortality and a high rate of permanent neurological sequelae (2)
    • most infections are asymptomatic (about one in 250 infections is estimated to become clinically apparent)
    • acute encephalitis is the most commonly recognized clinical manifestation of the disease (4)
    • in symptomatic cases the severity of the disease varies
      • mild disease is characterized by febrile headache or aseptic meningitis
      • illness usually begins with rapid onset and progression of fever, headache, and vomiting
      • over the next few days mental status of the patient changes and may develop focal neurologic deficits, generalized weakness, and movement disorders
      • Parkinson's-like syndrome with mask-like facies, tremor, cogwheel rigidity, and choreoathetoid movements are often seen
      • acute flaccid paralysis, with clinical and pathological features similar to those of poliomyelitis, has also been associated with JEV infection
      • seizures are common, especially among children.

Reference:


Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.