Management
- empirical antimicrobial therapy - consider:
- source of septicaemic organism, i.e. site
- neutropenia
- previous antibiotics
- any underlying disease
- prevailing patterns of antibiotic resistance
- whether hospital or community acquired
- oxygenation
- fluid replacement
- drainage of abscesses
- vasopressors and inotropes
New, currently experimental approaches:
- monoclonal antibodies to endotoxin
- monoclonal antibodies ot tissue mediators
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