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Pathology

Authoring team

The pathological features of osteoarthritis are:

  • progressive cartilage destruction
  • subarticular cysts - form in areas of greatest stress
  • subarticular sclerosis - trabeculae thickening around the cysts
  • osteophytosis - proliferation and ossification of cartilage in peripheral, unstressed areas
  • capsular fibrosis

Reference:

  • Glyn-Jones S, Palmer AJ, Agricola R, et al. Osteoarthritis. Lancet. 2015 Jul 25;386(9991):376-87

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