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Chronic active hepatitis (drug induced)

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Drug induced chronic hepatitis is a rare and idiosyncratic response to specific agent. There are some similarities to autoimmune chronic active hepatitis with auto-antibodies positive in many patients.

The hepatitis usually resolves upon withdrawal of the drug.

Drugs which have been implicated include:

  • isoniazid
  • methyldopa
  • nitrofurantoin
  • oxyphenisatin
  • dantrolene

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