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Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Preparations are named Sinemet a/b where 'a' is the dose in milligrams of carbidopa and 'b' the dose in milligrams of levodopa.

The initial dose is 100-125 mg levodopa 3-4 times daily

Maintenance usually 0.75-1.5 g total daily

The dose may need to be increased if a slow release preparation (Sinumet CR) is introduced.

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