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Depression (relationship with chronic fatigue syndrome)

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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  • patients with primary depression may have symptoms that resemble chronic fatigue syndrome (CFS); similarly patients with CFS may exhibit symptoms generally associated with depression

  • however studies on the clinical features and laboratory features of depression and CFS suggest that these diseases are distinct (1); CFS can generally be distinguished from somatisation disorder (2)


  • (1) Prescribers' Journal (2000), 40 (2), 99-106.
  • (2) Hickie I et al (1995). Can the chronic fatigue syndrome be defined by distinct clinical features? Psychol Med, 25, 925-35.

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