This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Pathology of Kuru

Authoring team

The histological appearances of Kuru are similar to those of Creutzfeldt-Jakob disease with a triad of spongiform vacuolation, neuronal loss and astrocytic proliferation.

These changes however predominantly affect the striatum and cerebellum. In addition however there are characteristic Kuru plaques of Amyloid containing a 27 kdalton prion protein, which are found inthe cerebellum in 60% of cases.

Reference:

  • Robbins Pathological Basis of Disease. Cotran, Kumar, Robbins 9th Edition, 2014

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2025 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.