Treatment and prognosis
Consult expert help.
Ensure good hydration.
Death occurs in the second or third decade from renal failure. Self-mutilation may be reduced by treatment with hydroxytryptophan. Allopurinol reduces uric acid levels, but it does not stop or delay the onset of neurological problems.
Reference:
- Nanagiri A. Lesch-Nyhan Syndrome. Treasure Island (FL): StatPearls Publishing. 2025 Jan.
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