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Antidepressants

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In contrast to irritable bowel syndrome, non-cardiac chest pain and depression there are no studies of the use of of tricyclic antidepressants in non-ulcer dyspepsia.

Tricylics may have a role in the treatment of non-ulcer dyspepsia either at low or full dose.

Reference:

  • (1) Efficacy of cisapride in the treatment of epigastric pain and concomitant symptoms in non-ulcer dyspepsia. Rosch, W. Scand. J. Gastroent. (1989) 165, 54-58
  • (2) Management of non-ulcer dyspepsia. Fisher, RS, Parkman, HP. New Engl J Med. (1998) 339, 1376-81

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