This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Midbrain signs

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Ocular abnormalities are a prominent feature of space- occupying lesions in the midbrain. Presentation includes:

  • lesions of the upper midbrain - weakness of conjugate deviation upwards and ptosis
  • lesions of the lower midbrain - weakness of conjugate deviation downwards - often accompanied by ptosis and weakness of convergence
  • pupils unequal and dilated
  • reactions to light and to convergence-accommodation may be both lost, or just the former may be absent
  • nuclear ophthalmoplegia may be asymmetrical
  • headache, papilloedema, vomiting from hydrocephalus
  • nystagmus and ataxia may result from injury to cerebellar pathways
  • compression of lateral lemniscus may cause unilateral or bilateral deafness
  • tremors, tonic convulsions, loss of consciousness may occur

Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.


Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.