Clinical presentations

There are a variety of characteristic presentations of myasthenia gravis: (1,2)

• Group I - ocular myasthenia gravis - symptoms remain confined to the ocular muscles.
• Group IIA, B - mild or moderately severe generalised myasthenia gravis
• Group III - acute severe disease with respiratory muscle involvement
• Group IV - late chronic disease - pelvic and lower limbs may be involved

Reference

1. Gilhus NE, Owe JF, Hoff JM, Romi F, Skeie GO, Aarli JA. Myasthenia gravis: a review of available treatment approaches. Autoimmune Dis. 2011;2011:847393.
2. Jaretzki A 3rd, Barohn RJ, Ernstoff RM, et al. Myasthenia gravis: recommendations for clinical research standards. Task Force of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America. Ann Thorac Surg. 2000 Jul;70(1):327-34.