This phenomenon consists of a sudden loss of anti-Parkinsonian effects of L-dopa and a resulting hypokinesia and rigidity. The loss of effectiveness of L-dopa therapy may last for several hours and can occur irregularly throughout the day.
It is a troublesome symptom which usually develops some time after the patient has been on L-dopa. It is not related to blood levels of L-dopa.
Consider:
Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page