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Aetiology

Authoring team

Causes of parkinsonian syndrome include: (1,2)

  • Parkinson’s disease
  • Alzheimer’s disease
  • multiple cerebral infarction
  • drug-induced parkinsonism (eg phenothiazines, metachlopramide)
  • other degenerative parkinsonian syndromes:
    • progressive supranuclear palsy
      • Steele–Richardson–Olszewski syndrome
    • multiple system atrophy
      • previously Shy–Drager syndrome
      • olivopontocerebellar atrophy
      • striatonigral degeneration
  • post-encephalitis
  • toxins:
    • carbon monoxide
    • copper
    • manganese
  • other:
    • trauma e.g. boxing
    • Wilson's disease

Reference:

  1. NICE. Parkinson’s disease in adults. NICE guideline NG71. Published July 2017, last reviewed December 2024
  2. Prachaya S et al. Parkinsonian syndromes. A review. Neurology India 66 (Suppl 1):p S15-S25, Mar–Apr 2018.

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