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Progressive supranuclear palsy

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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This is a loss of vertical and later of horizontal gaze, that is associated with:

  • pseudobulbar palsy
  • long tract signs
  • neck rigidity

The reflex eye movements on neck flexion and extension remain intact.

Males are more frequently affected than females and symptoms usually occur between the ages of 45 and 70 years.

There is no effective treatment and death usually occurs in five to ten years.

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