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Adverse effects

Authoring team

  • associated with gastrointestinal side effects including faecal urgency 22%, flatus with rectal discharge 24% and faecal incontinence 11%. Side effects increase if orlistat is taken with a high fat meal
  • clinical trial data revealed small decreases in serum vitamin A, D, E and beta carotene levels - in the majority of patients the levels remained within the normal range

Reference:

  1. Carter R, Mouralidarane A, Ray S, et al. Recent advancements in drug treatment of obesity. Clin Med. 2012 Oct;12(5):456-60.
  2. Filippatos TD, Derdemezis CS, Gazi IF, et al. Orlistat-associated adverse effects and drug interactions: a critical review. Drug Saf. 2008;31(1):53-65.

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