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Sibutramine

Authoring team

Sibutramine has been suspended in the UK amid fears that it increases the risk of heart attacks and strokes (1)

  • The European Medicines Agency (EMA) reviewed the obesity medicine sibutramine (Reductil) on the basis of safety information from a large clinical trial, the Sibutramine Cardiovascular OUTcomes (SCOUT) study. The review found that the cardiovascular risks of sibutramine outweigh its benefits. The EMA's Committee for Medicinal Products for Human Use (CHMP) recommended suspension of the marketing authorisation for this medicine across the European Union.

Reference:

1. Sibutramine: Suspension of marketing authorisation as risks outweigh benefits. Medicines and Healthcare products Regulatory Agency (MHRA), Jan 2010

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